In Interpol: The Trail of Dr. Chaos, players must track down a criminal mastermind and his villainous group as they embark on a sinister path of worldwide chaos and destruction. Gamers will travel around the globe as they unravel puzzles and gather hidden clues from exotic and remote locations, investigating elaborate crime scenes and overcoming treacherous mini-games along the journey. Game modes include single player storyline-based mode (local) and cooperative storyline-based mode (local or online).