Shadow of Destiny immerses players into the imaginative and chilling world of Eike Kusch, who is given the ability to time travel to prevent his own murder. The game features full character voiceovers, beautifully re-created European environments that change depending on the time period, and multiple story paths contingent upon the actions taken.

Gamers are offered a variety of puzzles and riddles that must be solved while searching for clues about the killer. In addition, Shadow of Destiny showcases over three hours of real-time cinematics that reveal the story across ten chapters, and contains additional scenarios that are unlocked when the game is replayed.