Professor Layton and the Azran Legacy follows Professor Hershel Layton and his assistants, Luke Triton and Emmy Altava, as they travel to the snow-laden city of Snowrassa to investigate a 'living mummy'. There, they find a girl named Aria, who comes from an ancient race known as the Azrans, frozen in ice. After freeing her and realizing she has lost her memory, their investigation takes them round the world as they search for the truth behind the mysterious Azran civilization and the hidden treasure it holds.