In a disorganized and ghostly city, those foolish, desperate, or unlucky enough to walk the streets lay prey to Britain’s most elusive predators: the vampires. Emerging from the chaos, a tormented figure awakens. You are Jonathan E. Reid, a high-ranking military surgeon transformed into a vampire upon his return home from the frontline.

Explore the darkly atmospheric streets of early 20th century London, and interact with a multitude of characters with their own identities and importance. Accept and fulfill the missions they give you, but don’t forget: sooner or later, you will have to feed, and make a difficult choice... who will be your prey? Absolutely all characters in the game are potential victims of your vampiric lust. Carefully study the habits of your next victim, his or her relationships with other characters, and set up your strategy to feed, unnoticed: seduce them, change their daily habits, or make sure they end up alone in a dark street...

Vampyr explores combat on the flu-ridden streets of 1918's London. All manner of dangers prowl London during a bout of the lethal Spanish Flu. From Vampire hunters to mutated abominations, Jonathan Reid will face foes as well as friends on his mission to discover the truth behind his new affliction. 

Armed with an array of conventional melee and ranged weaponry, attack and dodge foes to fill up Jonathan's Blood Gauge, required to unleash powerful vampire attacks. From impaling enemies on a spike, to draining them of blood at a distance, as Jonathan's Blood Gauge fills during a combat situation, his Vampire affliction will start to overtake his more human side, unleashing destructive spells and abilities against those who try to stop him. 

A non-linear skill tree will unlock through experience gained new, more powerful attacks and abilities. Jonathan is able to equip these abilities in any order, effectively allowing players to create their own archetypes to match their play-styles. Play aggressively and deal greater damage, or more securely, focusing on crowd-control and keeping enemies at bay. Skills can be evolved two different ways, for example, Spring, a skill that allows you to rush instantly to a distant enemy, can be developed to either deal area-of-effect damage or grant temporary invincibility. The choice is yours. 

Combat difficulty can be affected by player actions out of combat. Feeding on civilians provides a huge XP boost, which will make combat situations easier - but that comes with caveats; an increased danger on the streets, and narrative consequences for the world's citizens, to name a few. Full brawls are not the only options open to Doctor Reid, he can also stalk his prey, or even utilize his vampire speed and agility to avoid combat entirely. 

Players will have to investigate who to feed from, and who to spare, conscious of their need to increase their strength. Jonathan's Vampire impulses will always be working against his human side.

Be careful who you choose to hunt, as they will be gone forever, and their death will impact in a meaningful way the world that surrounds you. Feeding on human blood will not just keep you "alive"; it will also unlock new vampiric powers to use.

There will be times when exploration and seduction will only get you so far, and you'll need to resort to engaging in Vampyr's dynamic real-time combat. It blends hard-hitting melee combat with ranged shooting mechanics and the supernatural vampire powers. You'll face many types of enemies: different species of vampires and creatures, as well as vampire hunters who want to hunt you down with their weapons, tools and traps. In Vampyr, your health and the "energy" that drives your supernatural powers are one and same! Using powers will drain your own blood, giving you an edge in battle but also leaving you weaker. You will have to find a way to feed during combat to replenish your strength.

Vampyr also offers a deep crafting system. Find and loot materials and components from the fresh corpses of your victims or during exploration, in order to craft and improve tools, melee and ranged weapons, as well as special ammunitions and coating to exploit the weaknesses of your enemies.

As you cling to what remains of your humanity, your decisions will ultimately shape the fate of your hero while searching for answers in the coughing, foggy aftermath of the Spanish Flu.