Featuring an engrossing single-player campaign with lavishly gory details, Infected unlocks the world of Wi-Fi via exciting multiplayer modes. To participate in multiplayer combat, players create their own character or avatar. Those who are victorious in combat can "infect" the loser's PSP system with their avatar and gain ranking points. Avatars can be defeated through a variety of methods, as well as passed along from player to player thus creating a viral chain letter of attack.